IL4R (Human) Recombinant Protein (Q01)
产品名称： IL4R (Human) Recombinant Protein (Q01)
英文名称： IL4R (Human) Recombinant Protein (Q01)
产品编号： H00003566-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human IL4R partial ORF ( NP_000409, 26 a.a. - 135 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNV
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3566
- GeneBank Accession#:
- NM_000418
- Protein Accession#:
- NP_000409
- Gene Name:
- IL4R
- Gene Alias:
- CD124,IL4RA
- Gene Description:
- interleukin 4 receptor
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000122506,interleukin 4 receptor alpha chain,interleukin-4 receptor alpha chain
- Related Disease
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Adenocarcinoma
- Albuminuria
- Alveolar Bone Loss
- Alveolitis, Extrinsic Allergic
- Alzheimer Disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Arthritis, Juvenile Rheumatoid
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Bacterial Infections
- Blood Coagulation Disorders
- Brain Ischemia
- Brain Neoplasms