IKBKG monoclonal antibody (M02), clone 1D4
产品名称： IKBKG monoclonal antibody (M02), clone 1D4
英文名称： IKBKG monoclonal antibody (M02), clone 1D4
产品编号： H00008517-M02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant IKBKG.
- Immunogen:
- IKBKG (NP_003630, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLE
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- IKBKG monoclonal antibody (M02), clone 1D4 Western Blot analysis of IKBKG expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to IKBKG on HeLa cell . [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged IKBKG is approximately 3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 8517
- GeneBank Accession#:
- NM_003639
- Protein Accession#:
- NP_003630
- Gene Name:
- IKBKG
- Gene Alias:
- AMCBX1,FIP-3,FIP3,Fip3p,IKK-gamma,IP,IP1,IP2,IPD2,NEMO
- Gene Description:
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [supplied by RefSeq
- Other Designations:
- NFkappaB essential modulator,OTTHUMP00000026027,OTTHUMP00000026028,OTTHUMP00000026029,incontinentia pigmenti
- Gene Pathway
- Acute myeloid leukemia
- Adipocytokine signaling pathway
- Apoptosis
- B cell receptor signaling pathway
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Epithelial cell signaling in Helicobacter pylori infection
- MAPK signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Primary immunodeficiency
- Prostate cancer
- Small cell lung cancer
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway