Myozenin 2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Myozenin 2抗体

Myozenin 2抗体

商家询价

产品名称： Myozenin 2抗体

英文名称： Myozenin 2Antibody

产品编号： XY11450-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 MYOZENIN 2抗体Applications

In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 11450-1-AP;human brain tissuehuman brain tissue were subjected to SDS PAGE followed by western blot with 11450-1-AP(MYOZ2 antibody) at dilution of 1:400
Positive WB detected in Human brain tissue
Recommended dilution WB : 1:500-1:5000
 MYOZENIN 2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information MYOZENIN 2抗体
Immunogen Myozenin 2 fusion protein ag2008 Full name Myozenin 2
Calculated molecular
weight		 30 kDaa Observed molecular 
weight		 30-35kd
GenBank accession 
number		 BC017402 Gene ID (NCBI) 51778
Gene symbol MYOZ2 Synonyms C4orf5, Calsarcin-1, FATZ related protein 2, MYOZ2, Myozenin 2
Background

MYOZ2 gene encodes for the calcineurin-binding protein myozenin-2 (or Calsarcin-1) belonging to myozenin family. Defects in MYOZ2 gene are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder characterized by ventricular hypertrophy. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death (PMID: 17347475). Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, and gamma-filamin. Important role in the modulation of calcineurin signaling and myofibrillogenesis of myozenin-2 have been elucidated (PMID: 11114196). Proteintech’s Myozenin-2 antibody 11450-1-AP was raised against full-length protein of human origin and is able to detect band of approximate 34 kDa in Western blotting. MYOZENIN 2抗体

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