GNE polyclonal antibody (A01)
产品名称： GNE polyclonal antibody (A01)
英文名称： GNE polyclonal antibody (A01)
产品编号： H00010020-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant GNE.
- Immunogen:
- GNE (NP_005467, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag.
- Sequence:
- MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVH
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
- MSDS:
Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 10020
- GeneBank Accession#:
- NM_005476
- Protein Accession#:
- NP_005467
- Gene Name:
- GNE
- Gene Alias:
- DMRV,GLCNE,IBM2,NM,Uae1
- Gene Description:
- glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- N-acylmannosamine kinase,OTTHUMP00000021370,UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase,UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase
- Related Disease