FITC标记的FKBP2蛋白抗体
产品名称: FITC标记的FKBP2蛋白抗体
英文名称: Anti-FKBP2/FITC
产品编号: HZ-16094R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FKBP2/FITC Conjugated antibody
FITC标记的FKBP2蛋白抗体
英文名称 | Anti-FKBP2/FITC |
中文名称 | FITC标记的FKBP2蛋白抗体 |
别 名 | 13 kDa FK506-binding protein; 13 kDa FKBP; EC 5.2.1.8; FK506 binding protein 2 (13kD); FK506 binding protein 2 13kDa; FK506-binding protein 2; FKBP 13; FKBP 2; FKBP-13; FKBP-2; FKBP13; FKBP2; FKBP2_HUMAN; Immunophilin FKBP13; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP2; PPIase; PPIase FKBP2; Proline isomerase; Rapamycin binding protein; Rotamase. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 信号转导 转运蛋白 淋巴细胞 t-淋巴细胞 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 13kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FKBP2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: T-cells and thymus. Similarity: Belongs to the FKBP-type PPIase family. FKBP2 subfamily. Contains 1 PPIase FKBP-type domain. Database links: Entrez Gene: 2286 Human Entrez Gene: 14227 Mouse Omim: 186946 Human SwissProt: P26885 Human SwissProt: P45878 Mouse Unigene: 227729 Human Unigene: 4234 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白是免疫亲合蛋白家族的成员,在免疫调节和涉及蛋白折叠和转运的基本细胞过程中起作用。该编码蛋白是顺式反式脯氨酰异构酶,其结合免疫抑制剂FK506和雷帕霉素。它被认为是一个ER伴侣,也可以作为膜细胞骨架支架的一个组成部分。多个交替剪接变异体,编码相同的蛋白质,已被鉴定。[ RefSeq,SEP 2008提供]