FITC标记的生长因子受体结合适应蛋白抗体
产品名称： FITC标记的生长因子受体结合适应蛋白抗体
英文名称： Anti-GAPT/FITC
产品编号： HZ-13284R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GAPT/FITC Conjugated antibody
FITC标记的生长因子受体结合适应蛋白抗体
| 英文名称 | Anti-GAPT/FITC |
| 中文名称 | FITC标记的生长因子受体结合适应蛋白抗体 |
| 别 名 | C5orf29; Gapt; GAPT_HUMAN; Grb2-binding adaptor transmembrane; Growth factor receptor-bound protein 2-binding adapter protein; Growth factor receptor-bound protein 2-binding adapter protein, transmembrane; Protein GAPT; transmembrane. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 生长因子和激素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 18kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GAPT |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. The C5orf29 gene product has been provisionally designated C5orf29 pending further characterization. Function: Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells. Subunit: Interacts with GRB2. Subcellular Location: Cell membrane. Tissue Specificity: Highly expressed in spleen and PBL, detected at lower levels in thymus, and undetectable in all other tissues tested. Also expressed in various B-cell lines, monocytic cell line THP-1 and NK-like cell line YT, but not in T-cell line Jurkat or HeLa cells. Similarity: Belongs to the GAPT family. Database links: UniProtKB/Swiss-Prot: Q8N292.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
1亿8100万个碱基对编码约1000个基因，染色体5约为人类基因组DNA的6%。它通过ERCC8基因和家族性腺瘤性息肉病通过大肠腺瘤性息肉病（APC）肿瘤抑制基因与Cockayne综合征相关。Treacher Collins综合征也是5号染色体相关的，是由TCOF1基因内的插入或缺失引起的。5号染色体P臂缺失导致CRI—Douk综合征。在治疗相关的急性髓性白血病和骨髓增生异常综合征中，5q或5号染色体的缺失是常见的。c5Orf29基因产物已暂时指定为C5OF29，有待进一步鉴定。