TNFSF10 (Human) ELISA Kit
产品名称： TNFSF10 (Human) ELISA Kit
英文名称： TNFSF10 (Human) ELISA Kit
产品编号： KA0990
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- TNFSF10 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human TNFSF10.
- Calibration Range:
- 15.6 to 1000 pg/mL
- Limit of Detection:
- 1 pg/mL
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C for 4 months. For long term storage, please store at -20°C for 8 months.
- Quality Control Testing:
- Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Protocol:
Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Body Fluid, Cell Culture Supernatant, Plasma, Serum, Tissue Lysate
- Sample Volume:
- 100 uL
- Label:
- Biotin-conjugate
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Publication Reference
- 1.
- Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily.
Song JJ, Lee YJ.Cell Signal. 2008 May;20(5):892-906. Epub 2008 Jan 11.
- 2.
- Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.
Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A.J Biol Chem. 1996 May 31;271(22):12687-90.
- 3.
- Identification and characterization of a new member of the TNF family that induces apoptosis.
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA, et al..Immunity. 1995 Dec;3(6):673-82.
- Application Image
- Quantification
- Entrez GeneID:
- 8743
- Gene Name:
- TNFSF10
- Gene Alias:
- APO2L,Apo-2L,CD253,TL2,TRAIL
- Gene Description:
- tumor necrosis factor (ligand) superfamily, member 10
- Omim ID:
- 603598
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. [provided by RefSeq
- Other Designations:
- Apo-2 ligand,TNF-related apoptosis inducing ligand TRAIL,tumor necrosis factor (ligand) family, member 10,tumor necrosis factor apoptosis-inducing ligand splice variant delta
- Related Disease
- Breast Neoplasms
- Carcinoma, Ductal
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hematologic Diseases
- Hodgkin Disease
- Kidney Failure, Chronic
- Lupus Erythematosus, Systemic
- Lymphoproliferative Disorders
- Multiple Myeloma
- Multiple Sclerosis
- Neoplasm Recurrence, Local
- Neoplasms, Second Primary
- Occupational Diseases
- Ovarian Neoplasms
- Waldenstrom Macroglobulinemia
- Werner syndrome