GDF2 (N-term) Peptide
产品名称： GDF2 (N-term) Peptide
英文名称： GDF2 (N-term) Peptide
产品编号： P0856
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GDF2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human GDF2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1.
Majumdar MK, Wang E, Morris EA.J Cell Physiol. 2001 Dec;189(3):275-84.
- 2.
- Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9.
Lopez-Coviella I, Berse B, Krauss R, Thies RS, Blusztajn JK.Science. 2000 Jul 14;289(5477):313-6.
- 3.
- Bone morphogenetic protein-9. An autocrine/paracrine cytokine in the liver.
Miller AF, Harvey SA, Thies RS, Olson MS.J Biol Chem. 2000 Jun 16;275(24):17937-45.
- Applications
- Western Blot (Tissue lysate)
- The GDF2 polyclonal antibody (Cat # PAB3885) is used in Western blot to detect GDF2 in mouse liver tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with GDF2 polyclonal antibody (Cat # PAB3885) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
- Entrez GeneID:
- 2658
- Protein Accession#:
- Q9UK05
- Gene Name:
- GDF2
- Gene Alias:
- BMP-9,BMP9
- Gene Description:
- growth differentiation factor 2
- Omim ID:
- 605120
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019538,bone morphogenetic protein 9