TNF monoclonal antibody (M04), clone M2-E3
产品名称: TNF monoclonal antibody (M04), clone M2-E3
英文名称: TNF monoclonal antibody (M04), clone M2-E3
产品编号: H00007124-M04
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant TNF.
- Immunogen:
- TNF (AAH28148, 1 a.a. ~ 233 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (51.37 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged TNF is 0.1 ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 7124
- GeneBank Accession#:
- BC028148
- Protein Accession#:
- AAH28148
- Gene Name:
- TNF
- Gene Alias:
- DIF,TNF-alpha,TNFA,TNFSF2
- Gene Description:
- tumor necrosis factor (TNF superfamily, member 2)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq
- Other Designations:
- APC1 protein,OTTHUMP00000029281,OTTHUMP00000037669,TNF superfamily, member 2,TNF, macrophage-derived,TNF, monocyte-derived,cachectin,tumor necrosis factor alpha
- Gene Pathway
- Adipocytokine signaling pathway
- Allograft rejection
- Alzheimer's disease
- Amyotrophic lateral sclerosis (ALS)
- Apoptosis
- Asthma
- Cytokine-cytokine receptor interaction
- Fc epsilon RI signaling pathway
- Graft-versus-host disease
- Hematopoietic cell lineage
- Hypertrophic cardiomyopathy (HCM)
- MAPK signaling pathway
- Natural killer cell mediated cytotoxicity
- Systemic lupus erythematosus
- T cell receptor signaling pathway
- TGF-beta signaling pathway
- Toll-like receptor signaling pathway
- Type I diabetes mellitus
- Type II diabetes mellitus
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Abscess
- Absenteeism
- Acne Vulgaris
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Acute Lung Injury
- Adenocarcinoma
- Adenoma
- Adenomatous Polyps
- Adrenal Gland Neoplasms
- Aggressive Periodontitis
- AIDS Dementia Complex
- AIDS-Related Opportunistic Infections
- Albuminuria
- Alcoholism
- alpha 1-Antitrypsin Deficiency
- Alpha-1-antitrypsin deficiency