FITC标记的T淋巴细胞CD1D抗体
产品名称： FITC标记的T淋巴细胞CD1D抗体
英文名称： Anti-CD1d/FITC
产品编号： HZ-3690R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200
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Rabbit Anti-CD1d/FITC Conjugated antibody
FITC标记的T淋巴细胞CD1D抗体
| 英文名称 | Anti-CD1d/FITC |
| 中文名称 | FITC标记的T淋巴细胞CD1D抗体 |
| 别 名 | Antigen-presenting glycoprotein CD1d; CD1.1; CD1d; CD1D antigen; CD1D antigen d polypeptide; CD1d molecule; CD1D_HUMAN; Cd1d1; differentiation antigen CD1 alpha 3; HMC class I antigen like glycoprotein CD1D; Ly 38; MGC34622; R3; R3G1; T cell surface glycoprotein CD1d; Thymocyte antigen CD1D. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 信号转导 转录调节因子 细胞表面分子 t-淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | Flow-Cyt=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CD1D |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] Function: Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells. Subunit: Heterodimer with B2M (beta-2-microglobulin). Interacts with MHC II. Subcellular Location: Cell membrane, Single-pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Tissue Specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain Database links: Entrez Gene: 12479 Mouse Entrez Gene: 25109 Rat SwissProt: P11609 Mouse SwissProt: Q63493 Rat Unigene: 1894 Mouse Unigene: 11120 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
这个基因编码了发散member of the CD1家族的跨膜糖蛋白中，which are structurally related to the组织相容性复合体（MHC）和蛋白的形式heterodimers以及β2 -微球蛋白。the CD1蛋白介the Presentation of由脂质和糖脂抗原或微生物起源自对T细胞。人类基因组包含五CD1家族基因organized in a cluster我们1号染色体。CD1家庭members are thought to the differ in their细胞定位与特异性配体是脂质。the蛋白编码基因localizes by this to晚内涵体和溶酶体通过酪氨酸为基础的模式在胞质尾。两个变种不同的变形不同的异构体已经为这一基因进行了搜索。[ provided by RRRESEQ，Jan 2016 ]