FITC标记的钙粘蛋白29抗体
产品名称： FITC标记的钙粘蛋白29抗体
英文名称： Anti-CDH29/FITC
产品编号： HZ-13917R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-CDH29/FITC Conjugated antibody
FITC标记的钙粘蛋白29抗体
| 英文名称 | Anti-CDH29/FITC |
| 中文名称 | FITC标记的钙粘蛋白29抗体 |
| 别 名 | Cadherin-like protein 29; Cadherin-related family member 4; CDH29; CDHR4; CDHR4_HUMAN; UNQ9392/PRO34300; VLLR9392. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 细胞粘附分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Pig, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 86kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CDH29 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-29, also known as Cadherin-related family member 4, is a 788 amino acid single-pass type I membrane protein that has four cadherin domains. There are two isoforms of cadherin-29 that are produced as a result of alternative splicing events. The gene encoding cadherin-29 maps to human chromosome 3, which is is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Subcellular Location: Membrane. Tissue Specificity: Contains 4 cadherin domains. Similarity: Contains 4 cadherin domains. Database links: Entrez Gene: 389118 Human SwissProt: A6H8M9 Human Unigene: 363312 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
钙粘蛋白家族是一类Ca2+依赖的黏附分子，其作用是介导细胞与细胞结构的结合，维持结构和形态发生。钙粘蛋白各自在N端含有大量胞外域，其特征在于一系列五个同源重复，其中最远端被认为是负责结合特异性。钙粘蛋白-29，也称钙黏蛋白相关家族成员4，是具有四钙黏蛋白结构域的788氨基酸单程I型膜蛋白。有两种异构体的钙粘蛋白29，作为替代剪接事件的结果。编码钙粘蛋白-29的基因定位于人类3号染色体，其由约1100个基因编码的2亿1400万个碱基组成。值得注意的是，在第3号染色体上存在趋化因子受体基因簇和多种人类癌症相关基因座。染色体3短臂的特定区域在许多类型的癌细胞中被删除。