UNC5A-Specific抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
UNC5A-Specific抗体

UNC5A-Specific抗体

商家询价

产品名称： UNC5A-Specific抗体

英文名称： UNC5A-SpecificAntibody

产品编号： XY20239-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 UNC5A-SPECIFIC抗体Applications

In-house applications ELISA, WB, FC     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 20239-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 20239-1-AP(UNC5A-Specific antibody) at dilution of 1:100
  • 20239-1-AP;MCF-7 cells1X10^6 MCF-7 cells were stained with 0.2ug UNC5A-Specific antibody (20239-1-AP, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
Positive WB detected in Mouse brain tissue
Positive FC detected in MCF-7 cells
Recommended dilution WB : 1:200-1:1000
 UNC5A-SPECIFIC抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information UNC5A-SPECIFIC抗体
Immunogen Peptide Full name Unc-5 homolog A (C. elegans)
Calculated molecular
weight		 93 kDa Observed molecular 
weight		 103 kDa
GenBank accession 
number		 NM_133369 Gene ID (NCBI) 90249
Gene symbol UNC5A Synonyms FLJ16449, KIAA1976, Netrin receptor UNC5A, Protein unc 5 homolog 1, Protein unc 5 homolog A, unc 5 homolog A (C. elegans), UNC5A, UNC5H1
Background

UNC5A, also named as KIAA1976 and UNC5H1, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5A. It has no cross reaction to UNC5B, UNC5C and UNC5D. UNC5A-SPECIFIC抗体

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