FRS2 (Human) Recombinant Protein (Q01)
产品名称： FRS2 (Human) Recombinant Protein (Q01)
英文名称： FRS2 (Human) Recombinant Protein (Q01)
产品编号： H00010818-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human FRS2 partial ORF ( AAH21562.1, 1 a.a. - 341 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMSQEIMQNNSINVVEEPVVERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQ
- Theoretical MW (kDa):
- 63.14
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes.
Krejci P, Salazar L, Goodridge HS, Kashiwada TA, Schibler MJ, Jelinkova P, Thompson LM, Wilcox WR.J Cell Sci. 2008 Feb 1;121(Pt 3):272-81. Epub 2008 Jan 15.
- 2.
- Bisindolylmaleimide I suppresses FGF-mediated activation of ERK map kinase in chondrocytes by preventing SHP2 association with the FRS2 and GAB1 adaptor proteins.
Krejci P, Masri B, Salazar L, Farrington-Rock C, Prats H, Thompson LM, Wilcox WR.J Biol Chem. 2007 Feb 2;282(5):2929-36. Epub 2006 Dec 4.
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 10818
- GeneBank Accession#:
- BC021562
- Protein Accession#:
- AAH21562.1
- Gene Name:
- FRS2
- Gene Alias:
- FRS2A,FRS2alpha,SNT,SNT-1,SNT1
- Gene Description:
- fibroblast growth factor receptor substrate 2
- Omim ID:
- 607743
- Gene Ontology:
- Hyperlink
- Other Designations:
- FGFR signalling adaptor,suc1-associated neurotrophic factor target
- Gene Pathway
- Related Disease