CD28 monoclonal antibody, clone CD28.2 (PE)
产品名称: CD28 monoclonal antibody, clone CD28.2 (PE)
英文名称: CD28 monoclonal antibody, clone CD28.2 (PE)
产品编号: MAB6487
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against CD28.
- Immunogen:
- Native purified CD28 from DC28.1.3.3 hybridoma cells.
- Host:
- Mouse
- Theoretical MW (kDa):
- 44
- Reactivity:
- Human, Non-Human Primates
- Specificity:
- This antibody reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of MW 44 KDa) which is a critical costimulatory receptor of T cells.
- Form:
- Liquid
- Conjugation:
- PE
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates.
Jeong SH, Qiao M, Nascimbeni M, Hu Z, Rehermann B, Murthy K, Liang TJ.J Virol. 2004 Jul;78(13):6995-7003.
- 2.
- Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling.
Scharschmidt E, Wegener E, Heissmeyer V, Rao A, Krappmann D.Mol Cell Biol. 2004 May;24(9):3860-73.
- 3.
- Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6.
Marti F, Krause A, Post NH, Lyddane C, Dupont B, Sadelain M, King PD.J Immunol. 2001 Jan 1;166(1):197-206.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 940
- Gene Name:
- CD28
- Gene Alias:
- MGC138290,Tp44
- Gene Description:
- CD28 molecule
- Omim ID:
- 186760
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD28 costimulation is essential for CD4 (MIM 186940)-positive T-cell proliferation, survival, interleukin-2 (IL2; MIM 147680) production, and T-helper type-2 (Th2) development.[supplied by OMIM
- Other Designations:
- CD28 antigen,CD28 antigen (Tp44),T-cell-specific surface glycoprotein
- Related Disease
- Acute Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Behcet Syndrome
- Bronchiolitis, Viral
- Carcinoma, Squamous Cell
- Celiac Disease
- Cholangitis, Sclerosing
- Colon cancer
- Colorectal Neoplasms
- Diabetes Mellitus, Type 1
- Disease Progression
- Drug Eruptions
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hepatitis C
- Hodgkin Disease
- Hypersensitivity, Immediate