DNAJC1,DNAJC1蛋白抗体

产品编号HZ-14377R
英文名称DNAJC1
中文名称DNAJC1蛋白抗体
别 名DnaJ (Hsp40) homolog subfamily C member 1; DnaJ homolog subfamily C member 1; DnaJ like protein; DnaJ protein homolog MTJ1; Dnajc1; DNAJL1; DNJC1_HUMAN; ERdj1; HTJ1; MGC131954; MTJ1.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig,
DNAJC1,DNAJC1蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量59kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DNAJC1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DNAJC1,DNAJC1蛋白抗体PubMedPubMed
产品介绍background:
The DnaJ family comprises a group of chaperone proteins that contain a J domain and have diverse cellular localization and functions. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis and are also important mediators of proteolysis and protein degradation. DnaJC1 (DnaJ homolog subfamily C member 1), also designated MTJ1, HTJ1, ERdj1 or DNAJL1, is a 554 amino acid single-pass type I membrane protein found in the membrane of the endoplasmic reticulum, nucleus and microsome. DnaJC1 contains one J domain and two SANT domains, through which it interacts with GRP 78 and AACT, respectively. Via its cytosolic domain, DnaJC1 interacts with ribosomes and likely modulates protein synthesis. The gene encoding DnaJC1 maps to human chromosome 10p12.31 and mouse chromosome 2 A3.

Function:
May modulate protein synthesis.

Subcellular Location:
Endoplasmic reticulum membrane. Nucleus membrane. Microsome membrane.

Similarity:
Contains 1 J domain.
Contains 2 SANT domains.

Gene ID:
64215

DNAJC1,DNAJC1蛋白抗体Database links:
Entrez Gene: 64215 Human
Entrez Gene: 450344 Chimpanzee
Entrez Gene: 607587 Dog
Entrez Gene: 101125129 Gorilla
Entrez Gene: 13418 Mouse
Entrez Gene: 100455306 Orangutan
Entrez Gene: 100519794 Pig
Entrez Gene: 100341962 Rabbit
Entrez Gene: 291369 Rat
Entrez Gene: 704151 Rhesus monkey
Entrez Gene: 444260 Xenopus laevis
Entrez Gene: 496816 Xenopus tropicalis
Omim: 611207 Human
SwissProt: P82539 Dog
SwissProt: Q96KC8 Human
SwissProt: Q61712 Mouse
Unigene: 499000 Human
Unigene: 246674 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.