PAK3 monoclonal antibody (M07), clone 1H7
产品名称： PAK3 monoclonal antibody (M07), clone 1H7
英文名称： PAK3 monoclonal antibody (M07), clone 1H7
产品编号： H00005063-M07
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PAK3.
- Immunogen:
- PAK3 (NP_002569, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGE
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.53 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- A 14-3-3?^ dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIII?] to regulate post-Golgi carrier formation.
Valente C, Turacchio G, Mariggio S, Pagliuso A, Gaibisso R, Di Tullio G, Santoro M, Formiggini F, Spano S, Piccini D, Polishchuk RS, Colanzi A, Luini A, Corda D.Nat Cell Biol. 2012 Feb 26. doi: 10.1038/ncb2445. [Epub ahead of print]
- Applications
- Western Blot (Cell lysate)
- PAK3 monoclonal antibody (M07), clone 1H7 Western Blot analysis of PAK3 expression in NIH/3T3 ( Cat # L018V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to PAK3 on NIH/3T3 cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 5063
- GeneBank Accession#:
- NM_002578
- Protein Accession#:
- NP_002569
- Gene Name:
- PAK3
- Gene Alias:
- CDKN1A,MRX30,MRX47,OPHN3,PAK3beta,bPAK,hPAK3
- Gene Description:
- p21 protein (Cdc42/Rac)-activated kinase 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- OTTHUMP00000023855,OTTHUMP00000062894,beta-PAK,oligophrenin-3,p21 (CDKN1A)-activated kinase 3,p21-activated kinase 3,p21-activated kinase-3,serine/threonine-protein kinase PAK 3