PDXK (C-term) Peptide
产品名称： PDXK (C-term) Peptide
英文名称： PDXK (C-term) Peptide
产品编号： P2330
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PDXK.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PDXK.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Expression of cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog (mitochondrial precursor) in fetal Down syndrome brain.
Shin JH, Weitzdoerfer R, Fountoulakis M, Lubec G.Neurochem Int. 2004 Jul;45(1):73-9.
- 2.
- Human pyridoxal kinase: overexpression and properties of the recombinant enzyme.
Lee HS, Moon BJ, Choi SY, Kwon OS.Mol Cells. 2000 Aug 31;10(4):452-9.
- 3.
- Mechanisms of the inhibition of human erythrocyte pyridoxal kinase by drugs.
Laine-Cessac P, Cailleux A, Allain P.Biochem Pharmacol. 1997 Oct 15;54(8):863-70.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of PDXK polyclonal antibody (Cat # PAB2725) in HepG2 cell line lysate (35 ug/lane). PDXK (arrow) was detected using the purified polyclonal antibody (1 : 40 dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with PDXK polyclonal antibody (Cat # PAB2725) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 8566
- Protein Accession#:
- NP_003672;O00764
- Gene Name:
- PDXK
- Gene Alias:
- C21orf124,C21orf97,DKFZp566A071,FLJ31940,FLJ37311,MGC15873,MGC31754,MGC52346,PKH,PNK,PRED79
- Gene Description:
- pyridoxal (pyridoxine, vitamin B6) kinase
- Omim ID:
- 179020
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- pyridoxal kinase,pyridoxamine kinase,pyridoxine kinase,vitamin B6 kinase
- Gene Pathway
- Related Disease