FITC标记的杀菌/通透性增加蛋白样2抗体
产品名称： FITC标记的杀菌/通透性增加蛋白样2抗体
英文名称： Anti-BPIL2/FITC
产品编号： HZ-8424R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-BPIL2/FITC Conjugated antibody
FITC标记的杀菌/通透性增加蛋白样2抗体
| 产品编号 | bs-8424R-FITC |
| 英文名称 | Anti-BPIL2/FITC |
| 中文名称 | FITC标记的杀菌/通透性增加蛋白样2抗体 |
| 别 名 | BPIL 2; BPIL-2; bactericidal/permeability increasing protein like 2; BPIFC_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BPIL2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL2 (Bactericidal/permeability-increasing protein-like 2) is a 507 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL2 is expressed in the basal layer of inflamed epidermis from psoriasis patients, it is not detected in normal skin. Subcellular Location: Secreted (By similarity). Tissue Specificity: Detected in the basal layer of the epidermis from inflammatory skin from psoriasis patients, but not in normal skin. Similarity: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. Database links: UniProtKB/Swiss-Prot: Q8NFQ6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
杀菌/通透性增加蛋白家族的成员具有抗菌特性并结合亲脂性物质，因此靶向革兰氏阴性细菌。杀菌通透性增加蛋白（BPI）是多形核白细胞（中性粒细胞颗粒）中富含的抗菌和内毒素中和分子。与BPI、BPIL2（杀菌/通透性增加蛋白样2）共享结构和序列同源性是507氨基酸分泌蛋白，其包含两个半胱氨酸残基的共同保守特征，这两个半胱氨酸残基是蛋白质功能的关键。BPIR2在银屑病患者炎症表皮基底层表达，在正常皮肤中未检测到。