SIGLEC5 (Human) Recombinant Protein (Q01)
产品名称: SIGLEC5 (Human) Recombinant Protein (Q01)
英文名称: SIGLEC5 (Human) Recombinant Protein (Q01)
产品编号: H00008778-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Human SIGLEC5 partial ORF ( NP_003821, 465 a.a. - 549 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- RRKQAAGRPEKMDDEDPIMGTITSGSRKKPWPDSPGDQASPPGDAPPLEEQKELHYASLSFSEMKSREPKDQEAPSTTEYSEIKT
- Theoretical MW (kDa):
- 35.09
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 8778
- GeneBank Accession#:
- NM_003830
- Protein Accession#:
- NP_003821
- Gene Name:
- SIGLEC5
- Gene Alias:
- CD170,CD33L2,OB-BP2,OBBP2,SIGLEC-5
- Gene Description:
- sialic acid binding Ig-like lectin 5
- Omim ID:
- 604200
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The sialic acid-binding immunoglobulin-like lectins (SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin (Ig) superfamily that mediate protein-carbohydrate interactions. They specifically interact with sialic acids in glycoproteins and glycolipids, with each SIGLEC having a particular preference for both the nature of the sialic acid and its glycosidic linkage to adjacent sugars. SIGLECs have similar structures, including extracellular Ig-like domains composed of an N-terminal V-set domain followed by varying numbers of C2-set domains. It appears that all SIGLECs have an unusual arrangement of conserved cysteine residues in the V-set and adjacent C2-set domains. Most SIGLECs are expressed uniquely within the hematopoietic system (Cornish et al., 1998 [PubMed 9731071]).[supplied by OMIM
- Other Designations:
- CD33 antigen-like 2,OB binding protein-2,sialic acid-binding immunoglobulin-like lectin 5